Do not upgrade yet to El Capitan OS if you use After Effects a lot. When working on networked files it slows to an unworkable speed.
I’ve been on it for a while, but have only just noticed this as I’ve only been working in Maya recently and that is fine.
It appears to be a major issue involving smb sharing and whatnot. There’s some people discussing it here.
I’m just downloading an upgrade for AE now so will keep you informed.